发明名称 |
SUSTAINED-RELEASE FORMULATIONS OF COLCHICINE AND METHODS OF USING SAME |
摘要 |
Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined or desired release profile. Method of treating or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein is also provided. |
申请公布号 |
US2016081936(A1) |
申请公布日期 |
2016.03.24 |
申请号 |
US201414784596 |
申请日期 |
2014.04.16 |
申请人 |
MURRAY AND POOLE ENTERPRISES LIMITED |
发明人 |
Riel Susanne |
分类号 |
A61K9/20;A61K45/06;A61K31/165 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
|
主权项 |
1. A sustained release formulation of colchicine as an active ingredient, the formulation comprising:
(a) colchicine or a pharmaceutically acceptable salt thereof; (b) a retarding agent; and (c) at least one pharmaceutically acceptable excipient. |
地址 |
Gibraltar GB |