| 发明名称 |
PHENYL QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS |
| 摘要 |
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, B, W1, W2, W3, and R1-R8 are described herein. |
| 申请公布号 |
WO2016044782(A1) |
申请公布日期 |
2016.03.24 |
| 申请号 |
WO2015US51046 |
申请日期 |
2015.09.18 |
| 申请人 |
FORMA THERAPEUTICS, INC. |
发明人 |
ASHWELL, SUSAN;CAMPBELL, ANN-MARIE;CARAVELLA, JUSTIN ANDREW;DIEBOLD, R. BRUCE;ERICSSON, ANNA;GUSTAFSON, GARY;LANCIA, DAVID R.;LIN, JIAN;LU, WEI;WANG, ZHONGGUO |
| 分类号 |
C07D401/12;A61K31/4704;A61K31/4709;A61P35/00;C07D215/227;C07D405/12;C07D409/12;C07D471/04 |
主分类号 |
C07D401/12 |
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