OSTEOINDUCTIVE SUBSTRATES AND METHODS OF MAKING THE SAME

摘要

Systems and methods for preparing osteoinductive synthetic bone grafts are provided in which a porous ceramic granule is loaded with an osteoinductive material, and then placed in contact with a biocompatible matrix material.

主权项

1. A method of making an osteoinductive scaffold, the method comprising:
contacting a calcium ceramic granule with a solution comprising an osteoinductive material, thereby associating the osteoinductive material with an interior surface of the ceramic granule; and placing the granule within a biocompatible matrix.