COMPOSITIONS AND METHODS FOR TREATING CARDIOMETABOLIC DISEASES AND DISORDERS

摘要

Described herein are combinations useful for treating or preventing a cardiometabolic disease or disorder, or which can be used for appetite suppression, for improvement of endothelial function, for controlling weight, or a combination of one or more thereof. The combinations comprise Berberine, alpha lipoic acid (LA), and apocynin, or an isomer, derivative, pharmaceutically acceptable salt or ester of one or more thereof. Methods of treatment using the combinations, as well as compositions and re lated medical uses are also described.

主权项

1. A combination for treating or preventing a cardiometabolic disease or disorder, for appetite suppression, for improvement of endothelial function, for controlling weight, or for one or more thereof in a subject, said combination comprising:
Berberine, an isomer, derivative, pharmaceutically acceptable salt or ester thereof, alpha lipoic acid (LA), an isomer, derivative, pharmaceutically acceptable salt or ester thereof, and a source of apocynin, an isomer, derivative, pharmaceutically acceptable salt or ester thereof.