发明名称 DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE
摘要 PROBLEM TO BE SOLVED: To provide a novel compound that is a sodium-dependent phosphate transporter inhibitor, useful for developing a preventive and/or therapeutic agent for hyperphosphatemia, secondary hyperparathyroidism, and chronic renal failure, and a method for prevention and/or treatment.SOLUTION: Provided are a dihydropyridazine-3,5-dione derivative represented by formula (I), a salt thereof, and solvates of them. [R1, R4 and R5 represent H, alkyl, or together form cycloalkyl or the like; R3 is a C1-10 alkyl or the like; Ar1 is a C6-10 aryl or 5-10 membered heteroaryl].SELECTED DRAWING: None
申请公布号 JP2016040262(A) 申请公布日期 2016.03.24
申请号 JP20150182722 申请日期 2015.09.16
申请人 CHUGAI PHARMACEUT CO LTD 发明人 OTAKE YOSHIHITO;OKAMOTO NAOKI;ONO YOSHIYUKI;KASHIWAGI HIROTAKA;KIMBARA ATSUSHI;HARADA TAKEO;HORI NOBUYUKI;MURATA YOSHIHISA;TACHIBANA KAZUO;TANAKA SHOTA;NOMURA KENICHI;IDE MITSUAKI;MIZUGUCHI EISAKU;ICHIDA YASUHIRO;OTOMO SHUICHI;HORIBA NAOSHI
分类号 C07D237/04;C07D401/12;C07D401/14;C07D403/12;C07D407/14;C07D413/14;C07D471/04;C07D487/04;C07D487/08;C07D498/08 主分类号 C07D237/04
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