发明名称 |
MONOCLONAL ANTIBODY AGAINST HUMAN TAU PROTEIN |
摘要 |
The invention relates to the monoclonal antibody 1G2, the hybridoma cell line H-1 G2 characterized by DSM ACC3248, and the epitope TPP comprising the amino acids tryptophan, proline, proline. The invention further relates to a method for producing a monoclonal antibody against a TAU protein fraction that is non-phosphorylated in positions T175 and/or T181 and/or T231. The invention also describes uses of the monoclonal antibody 1 G2 as well as an immunochemical detection system and the uses thereof. The invention finally describes the use of the immunochemical detection system for diagnosing Alzheimer's disease in humans. |
申请公布号 |
WO2016041553(A2) |
申请公布日期 |
2016.03.24 |
申请号 |
WO2015DE100394 |
申请日期 |
2015.09.17 |
申请人 |
AJ ROBOSCREEN GMBH |
发明人 |
LACHMANN, INGOLF;HOLZER, MAX;LEWCZUK, PIOTR;KORNHUBER, JOHANNES;PERRET-LIAUDET, ARMAND;FLACH, KATHARINA |
分类号 |
C07K16/18 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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地址 |
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