发明名称 HAT INHIBITORS AND METHODS FOR THEIR USE
摘要 Compounds having a structure of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R3c, R4a, R4b, R5, R6, Z and X are as defined herein are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.
申请公布号 WO2016044777(A1) 申请公布日期 2016.03.24
申请号 WO2015US51040 申请日期 2015.09.18
申请人 ABBVIE INC. 发明人 KESICKI, EDWARD A.;WANG, CE;PATANE, MICHAEL A.;KLUGE, ARTHUR F.;VAN DRIE, JR., JOHN H.
分类号 C07D405/14;A61K31/4166;A61K31/4178;A61K31/421;A61K31/422;A61P3/00;A61P25/28;A61P29/00;A61P35/00;C07D233/74;C07D233/76;C07D233/78;C07D263/44;C07D401/04;C07D403/04;C07D403/06;C07D403/14;C07D405/04;C07D405/12;C07D409/04;C07D413/04 主分类号 C07D405/14
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