Method and System for Treatment of Damaged Biological Tissue

摘要

Biomaterial compositions and articles comprising mesothelial tissue and a glycosaminoglycan (GAG), for treating damaged biological tissue; particularly, damaged cardiovascular tissue. The biomaterial compositions and articles can also include additional biologically active agents, such as growth factors. The biomaterial compositions and articles induce modulated healing, including modulation of inflammation and induced neovascularization when administered to damaged biological tissue.

主权项

1. A composition for treating damaged biological tissue, comprising:
an extracellular matrix (ECM) composition comprising acellular mesothelial tissue and a supplemental biologically active agent, said supplemental biologically active agent comprising a glycosaminoglycan (GAG), wherein, when said ECM composition is administered to said damaged biological tissue, said ECM composition induces modulated healing, said modulated healing comprising modulation of inflammation and induced bioremodeling and regeneration of new biological tissue.