摘要 |
A pharmaceutical composition containing an analgesic agent and an antispasmodic agent is disclosed, with ketorolac tromethamine as the analgesic agent, which is physically isolated from the antispasmodic agent, the antispasmodic agent which is combined with the analgesic agent, ketorolac tromethamine, being hyoscine, pargeverine, tolterodine, mebeverine or papaverine. Both the analgesic agent, ketorolac tromethamine, and the antispasmodic agent are combined in a separate, immediate release form. The analgesic agent, ketorolac tromethamine, can also be found in the present combination in a separate, immediate release form, while the antispasmodic agent in the combination is likewise in a separate form, but having a programmed release. The proportion by weight of the active ingredient, ketorolac tromethamine, ranges from 2.5% to 20%, and the proportion by weight of the active antispasmodic ingredient ranges from 2.5% to 20%. |
申请人 |
DIFFUCAP CHEMOBRAS QUÍMICA E FARMACÉUTICAL LTDA;ABRAMOWICZ, JAIME;SOUZA, FERNANDO RAFAEL DE;MARTINS, CARLOS ANTONIO |
发明人 |
ABRAMOWICZ, JAIME;SOUZA, FERNANDO RAFAEL DE;MARTINS, CARLOS ANTONIO |