TREATMENT OF NEURODEGENERATIVE DISEASES WITH COMBINATION OF LAQUINIMOD AND FINGOLIMOD
摘要
This invention provides a method of treating a subject afflicted with a neurodegenerative disease comprising periodic administration of an amount of laquinimod and an amount of fingolimod, wherein the amounts when taken together are effective to treat the subject. Also provided are packages and pharmaceutical compositions comprising laquinimod and fingolimod for treating a subject afflicted with a neurodegenerative disease. Also provided is a pharmaceutical composition comprising laquinimod for use as an add-on therapy or in combination with fingolimod, and a pharmaceutical composition comprising fingolimod for use as an add-on therapy or in combination with laquinimod, for treating said subject.
申请公布号
WO2016044103(A1)
申请公布日期
2016.03.24
申请号
WO2015US49799
申请日期
2015.09.11
申请人
TEVA PHARMACEUTICAL INDUSTRIES LTD.;TEVA PHARMACEUTICALS USA, INC.;HAYDEN, MICHAEL;HAYARDENY, LIAT;LADKANI, DAVID