主权项 |
1. A cover (10) for use in a digital microfluidics system (16) for manipulating samples in liquid portions or droplets; the digital microfluidics system (16) comprising a first substrate (18) and a central control unit (20), wherein said first substrate (18) comprises an array of electrodes (24), and wherein said central control unit (20) is in operative connection to said electrodes for controlling the selection of individual electrodes (22) thereof and for providing a number of said electrodes with voltage for manipulating liquid portions or droplets by electrowetting; in said digital microfluidics system (16), a working gap (30) with a gap height is located parallel to the array of electrodes (24) and in-between first and second hydrophobic surfaces (26,28); the two hydrophobic surfaces (26,28) facing each other at least during operation of the digital microfluidics system (16),
wherein the cover (10) comprises on one side the second hydrophobic surface (28) and on another side at least one micro-container interface (32) for safe introducing into and/or withdrawing of liquids from the gap (30); said at least one micro-container interface (32) comprising at least one cone (34), the inner surface thereof being formed such to provide a sealing form fit contact with an outer surface of an inserted micro-container nozzle (36), by which a liquid (48) is transferrable through a fluidic access hole (38) formed into the cover (10) and interconnecting each cone (34) and the gap (30). |