发明名称 |
REPOPULATION OF ORGANS AND TISSUES USING A YAP-ERT2 FUSION PROTEIN |
摘要 |
Provided herein are methods for the repopulation of organs and tissues, such as the liver, using modified cells that express a transcription coactivation factor-ligand binding domain fusion protein, such as a YAP-ERT2 fusion protein. Also provided are compositions, including nucleic acid molecules that encode a YAP-ERT2 fusion protein, YAP-ERT2 fusion polypeptides, and cells containing nucleic acid molecules that encode a YAP-ERT2 fusion protein. |
申请公布号 |
WO2016044096(A1) |
申请公布日期 |
2016.03.24 |
申请号 |
WO2015US49768 |
申请日期 |
2015.09.11 |
申请人 |
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY |
发明人 |
SHAFRITZ, DAVID, A.;YOVCHEV, MLADEN, I. |
分类号 |
C07K16/28;C07K14/705;C07K14/82 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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