The present disclosure pertains to detection of biomarkers in a sample. More particularly, the disclosure relates to methods for treating the sample to liberate certain analytes prior to the assay. Composition for disrupting the HIV virus and antibody-antigen complex to release p24 antigen is also disclosed. The disclosed methods and compositions are compatible with existing HIV antigen/antibody combination assays and improve the sensitivity of such assays.
申请公布号
EP2893347(A4)
申请公布日期
2016.03.23
申请号
EP20130835431
申请日期
2013.09.04
申请人
MBIO DIAGNOSTICS INC.
发明人
MYATT, CHRISTOPHER, J.;NIEUWLANDT, DANIEL, T.;HUSAR, GREGORY, MCLINTOCK;GREEF, CHARLES, H.