发明名称 |
NOVEL MONOCLONAL ANTIBODY WHICH IS SPECIFICALLY BOUND TO TM4SF5 PROTEIN AND USE THEREOF |
摘要 |
The present invention relates to a novel monoclonal antibody which is specifically bound to a transmembrane 4 L six family member 5 (TM4SF5) protein. More particularly, the present invention relates to a monoclonal antibody which is specifically bound to a human TM4SF5 protein, to polynucleotides coding for the monoclonal antibody, to an expression vector comprising the nucleotides, to a transformant with the vector introduced thereto, to a method for preparing the monoclonal antibody, to a composition comprising the monoclonal antibody, to a method for treating cancer using the monoclonal antibody, to a method for inhibiting liver metastasis of cancer, to a method for diagnosing cancer using the monoclonal antibody and to a cancer diagnosis kit comprising the monoclonal antibody. |
申请公布号 |
EP2886556(A4) |
申请公布日期 |
2016.03.23 |
申请号 |
EP20130824875 |
申请日期 |
2013.08.05 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;SNU R&DB FOUNDATION |
发明人 |
KIM, SE MI;KIM, SANG JICK;MIN, HYE JIN;SONG, JIN MYEONG;LEE, JUNG WEON;KIM, HYE JIN;AHN, HYE MI;CHOI, IN PYO;RYU, JI HYE |
分类号 |
C07K16/28;A61K39/395;A61P35/00;G01N33/574 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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