发明名称 NOVEL MONOCLONAL ANTIBODY WHICH IS SPECIFICALLY BOUND TO TM4SF5 PROTEIN AND USE THEREOF
摘要 The present invention relates to a novel monoclonal antibody which is specifically bound to a transmembrane 4 L six family member 5 (TM4SF5) protein. More particularly, the present invention relates to a monoclonal antibody which is specifically bound to a human TM4SF5 protein, to polynucleotides coding for the monoclonal antibody, to an expression vector comprising the nucleotides, to a transformant with the vector introduced thereto, to a method for preparing the monoclonal antibody, to a composition comprising the monoclonal antibody, to a method for treating cancer using the monoclonal antibody, to a method for inhibiting liver metastasis of cancer, to a method for diagnosing cancer using the monoclonal antibody and to a cancer diagnosis kit comprising the monoclonal antibody.
申请公布号 EP2886556(A4) 申请公布日期 2016.03.23
申请号 EP20130824875 申请日期 2013.08.05
申请人 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;SNU R&DB FOUNDATION 发明人 KIM, SE MI;KIM, SANG JICK;MIN, HYE JIN;SONG, JIN MYEONG;LEE, JUNG WEON;KIM, HYE JIN;AHN, HYE MI;CHOI, IN PYO;RYU, JI HYE
分类号 C07K16/28;A61K39/395;A61P35/00;G01N33/574 主分类号 C07K16/28
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