The present disclosure provides immunogenic compositions comprising HCV E1, E2, or E1/E2 polypeptides from two or more different HCV genotypes. The present disclosure provides immunogenic compositions comprising HCV E2 or E1/E2 polypeptides from two or more different HCV genotypes. The immunogenic compositions are useful in carrying out methods of inducing an immune response to HCV. The present disclosure further provides methods of stimulating an immune response to HCV in an individual.
申请公布号
EP2996718(A1)
申请公布日期
2016.03.23
申请号
EP20140884476
申请日期
2014.05.15
申请人
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
发明人
HOUGHTON, MICHAEL;HOCKMAN, DARREN;LAW, JOHN, L.;LOGAN, MICHAEL;TYRRELL, LORNE D.