发明名称 CHIMERIC PROTEIN BINDING TO ANGIOGENIC FACTOR
摘要 PROBLEM TO BE SOLVED: To provide a chimeric protein having antiangiogenic effect.SOLUTION: The present invention relates to a chimeric protein that has an extracellular domain of BMP-9 type I cell surface receptor and an extracellular domain of VEGF on-cell membrane receptor and binds to BMP-9 and VEGF, DNA encoding the chimeric protein, a vector having the DNA encoding the chimeric protein, a cell that expresses the chimeric protein, and a pharmaceutical composition comprising the chimeric protein.SELECTED DRAWING: None
申请公布号 JP2016036322(A) 申请公布日期 2016.03.22
申请号 JP20140163804 申请日期 2014.08.11
申请人 NIPPON KAYAKU CO LTD;UNIV OF TOKYO 发明人 AKATSU YUICHI;MIYAZONO KOHEI;WATABE TETSUO
分类号 C12N15/09;A61K31/7088;A61K35/76;A61K38/00;A61K48/00;A61P9/14;A61P35/00;A61P43/00;C07K14/705;C07K16/18;C07K19/00;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12P21/02;C12P21/08 主分类号 C12N15/09
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