发明名称 Method for measuring calcineurin activity
摘要 The present invention relates to a method for measuring the activity of calcineurin in a biological sample wherein a kinase inhibitor is present in the assay reaction mix.
申请公布号 US9290792(B2) 申请公布日期 2016.03.22
申请号 US201314381533 申请日期 2013.02.14
申请人 UNIVERSITE PARIS DESCARTES;ASSISTANCE PUBLIQUE HOPITAUX DE PARIS 发明人 Sanquer Sylvia;Barouki Robert;Herry Laurence
分类号 C12Q1/42 主分类号 C12Q1/42
代理机构 Marshall, Gerstein & Borun LLP 代理人 Marshall, Gerstein & Borun LLP
主权项 1. A method for measuring the activity of calcineurin in a biological sample comprising the steps of: providing a reaction mix comprising a substrate, at least one phosphatase inhibitor and at least one kinase inhibitor; incubating said biological sample with the reaction mix under conditions suitable for the activity of calcineurin; measuring the amount of dephosphorylated substrate.
地址 Paris FR