Cosmetic base comprising collagen-modified liposome and skin cosmetic containing the same

摘要

The affinity of collagen for the skin and its persistence on the skin are improved without destroying the triple helical structure inherent in collagen to thereby improve its ability to retain the moisture of the skin and increase the amount of bound water when such collagen is used as a skin cosmetic. The collagen can thereby exert its moisture retention effect more effectively. A cosmetic base includes an aqueous solution of a liposome that is surface-modified with water-soluble collagen having a triple helical structure.

主权项

1. A method for producing a cosmetic base which promotes permeation of a collagen into a stratum corneum of skin and which, in an environment at a temperature of 20° C. or less comprises the following steps:
(1) preparing an aqueous solution of a liposome controlled to have a positive or negative surface charge by a charge of a film-forming material; (2) dropping into the aqueous solution of (1) a water-soluble collagen which is controlled to have a charge opposite to the charge of the liposome, while retaining a triple helical structure, and which is to be adsorbed on the surface of the liposome, to form a mixture; and (3) stirring the mixture of (2) for the water-soluble collagen to be adsorbed on the surface of the liposome by electrostatic force.