| 发明名称 |
AAV VIRIONS WITH DECREASED IMMUNOREACTIVITY AND USES THEREFOR |
| 摘要 |
Methods of making and using recombinant AAV virions with decreased immunoreactivity are described. The recombinant AAV virions include mutated capsid proteins or are derived from non-primate mammalian AAV serotypes and isolates that display decreased immunoreactivity relative to AAV-2. |
| 申请公布号 |
PT1633772(E) |
申请公布日期 |
2016.03.22 |
| 申请号 |
PT20040755800T |
申请日期 |
2004.06.21 |
| 申请人 |
AVIGEN, INC. |
发明人 |
ALEJANDRA ELENA ARBETMAN;PETER COLOSI;MICHAEL A. LOCHRIE;SUROSKY, RICHARD T. |
| 分类号 |
C07K1/00;A61K;C07K14/00;C07K14/15;C07K17/00;C12N15/00;C12N15/09;C12N15/63;C12N15/70;C12N15/74;C12N15/864 |
主分类号 |
C07K1/00 |
| 代理机构 |
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代理人 |
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