发明名称 |
Antibacterial cyclopenta[c]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones |
摘要 |
The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.; |
申请公布号 |
US9290493(B2) |
申请公布日期 |
2016.03.22 |
申请号 |
US201414552108 |
申请日期 |
2014.11.24 |
申请人 |
Janssen Sciences Ireland UC |
发明人 |
Guillemont Jerome Emile Georges;Lancois David Francis Alain;Motte Magali Madeleine Simone;Koul Anil;Balemans Wendy Mia Albert;Arnoult Eric Pierre Alexandre |
分类号 |
C07D471/00;C07D487/00;C07D471/02;A61K31/50;A61K31/495;A61K31/44;C07D471/04;C07D487/04;C07D519/00 |
主分类号 |
C07D471/00 |
代理机构 |
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代理人 |
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主权项 |
1. A compound selected from the group consisting of:and pharmaceutically acceptable salts thereof. |
地址 |
Co, Cork IE |