| 摘要 |
A method is disclosed for generating sinograms by sampling a plurality of transducers acoustically coupled with the surface of a volume of tissue over a period of time after a light pulse at one wavelength, and after another light pulse at a different wavelength, and for processing those sinograms, reconstructing at least two optoacoustic images from the two sinograms, processing the two optoacoustic images to generate two envelope images and generating a parametric map from information in the two envelope images. In an embodiment, motion and tracking are determined to align the envelope images. In an embodiment, at least a second parametric map is produced from information in the same two envelope images. In an embodiment an ultrasound image is also acquired, and the parametric map is coregistered with and overlayed upon the ultrasound image, and then displayed. |
| 主权项 |
1. A method comprising the steps of:
generating a plurality of sinograms, each being generated by sampling a plurality of transducers acoustically coupled with a surface of a volume for a predetermined period of time after a pulse of light having a predominant wavelength selected from at least two different predominant wavelengths, each transducer being associated with a channel in an optoacoustic imaging system; processing at least two sinograms, each corresponding to a different one of the at least two different predominant wavelengths to create at least two processed sinograms, the processing comprising one or more steps selected from the group consisting of: mitigating anomalous channels, mitigating common mode stripes, bandpass filtering, mitigating the system transfer function, normalization of dynamic range, normalization of energy, removal of interframe persistent artifacts, compensating for hardware time gain compensation, performing sub-band acoustic compensation, and applying a transform operator; performing image reconstruction based upon the at least two processed sinograms to generate at least two optoacoustic images, the image reconstruction comprising one or more steps selected from the group consisting of: extract quadrature, sub-band acoustic compensation, and reconstruction; performing image post processing on the at least two optoacoustic images to generate at least two envelope images, the image post processing comprising one or more steps selected from the group consisting of: removing interframe persistent artifacts, fluence compensation and complex magnitude; generating at least one parametric map based upon the information contained in each of the at least two envelope images; generating an additional parametric map based upon the information contained in each of the at least two envelope images; and, generating a third parametric map, the third parametric map reflective of a combination of information in the at least one parametric map and the additional parametric map. |
