发明名称 |
Methods for making and using novel semi-synthetic small molecules for the treatment parasitic disease |
摘要 |
Small molecule therapeutics for the treatment of parasitic diseases, in particular, semi-synthetic derivatives of the fungally-derived natural product merulin A for the treatment of African Sleeping Sickness. |
申请公布号 |
US9290474(B2) |
申请公布日期 |
2016.03.22 |
申请号 |
US201414574092 |
申请日期 |
2014.12.17 |
申请人 |
The Regents of the University of California |
发明人 |
Linington Roger R;Navarro Gabriel;Pudhom Khanitha;McKerrow James |
分类号 |
C07D319/02;C07D311/02;C07D405/12;C07D407/12;C07D409/12;C07D413/12;C07D417/12 |
主分类号 |
C07D319/02 |
代理机构 |
|
代理人 |
Bell Adam Warwick;Kaser Matthew Rupert |
主权项 |
1. A method for producing compounds of the formulae the method comprising esterification of Merulin A. |
地址 |
Oakland CA US |