发明名称 |
Myocardial perfusion imaging methods and compositions |
摘要 |
A myocardial imaging method that is accomplished by administering one or more adenosine A2A adenosine receptor agonist to a human undergoing myocardial imaging as well as pharmaceutical compositions comprising at least one A2a receptor agonist, at least one liquid carrier, and at least one co-solvent. |
申请公布号 |
US9289446(B2) |
申请公布日期 |
2016.03.22 |
申请号 |
US201414533025 |
申请日期 |
2014.11.04 |
申请人 |
Gilead Sciences, Inc. |
发明人 |
Belardinelli Luiz;Rosner Mitchell |
分类号 |
A01N43/04;A61K31/70;A61K51/00;A61K49/00;A61K31/7076;A61K51/04;A61K47/10 |
主分类号 |
A01N43/04 |
代理机构 |
Sheppard Mullin Richter & Hampton LLP |
代理人 |
Sheppard Mullin Richter & Hampton LLP |
主权项 |
1. A pharmaceutical composition comprising:
a) about 400 μg of a compound which has the formula: b) at least one liquid carrier selected from the group consisting of water, saline, a buffer, and combinations thereof, c) at least one sodium phosphate buffer; d) EDTA; and e) propylene glycol in an amount of about 15% (w:v),wherein the pH of said pharmaceutical composition is from about 6 to about 8. |
地址 |
Foster City CA US |