发明名称 |
Imaging beta cell mass |
摘要 |
The present disclosure provides compositions and methods based on peptide-detectable agent conjugates that are useful for imaging beta cell mass. |
申请公布号 |
US9289516(B2) |
申请公布日期 |
2016.03.22 |
申请号 |
US201114003959 |
申请日期 |
2011.06.27 |
申请人 |
The General Hospital Corporation |
发明人 |
Weissleder Ralph;Reiner Thomas;Keliher Edmund J. |
分类号 |
A61K38/00;C07K2/00;A61K49/00;A61K51/08 |
主分类号 |
A61K38/00 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A composition comprising the peptide sequence SEQ ID NO:2, wherein the amino acid at position 12 is an unnatural amino acid, wherein the unnatural amino acid is (S)-2-amino-4-pentynoic acid. |
地址 |
Boston MA US |