THERAPEUTIC COMPOSITION WITH A BOTULINUM NEUROTOXIN

摘要

The present invention pertains to pharmaceutical compositions which comprise botulinum toxin from Clostridium botulinum. The pharmaceutical compositions of the instant invention are not only free of a mammalian derived proteinaceous stabilizing agent but are free of any stabilizing protein.

主权项

1. A pharmaceutical composition comprising botulinum toxin complexes from Clostridium botulinum of type A, B, C1, D, E, F or G or a mixture of two or more Clostridium botulinum toxin types, a non-proteinaceous stabilizing agent for the botulinum toxin complexes selected from hyaluronic acid, polyvinylpyrrolidone and polyethyleneglycol, and, optionally, a pH buffer and/or a cryoprotectant, wherein the pharmaceutical composition is free of any stabilizing protein.