发明名称 POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS
摘要 Microemulsions and soluble alkali metal salts of relatively insoluble aglycone polyphenols within oral hygienic products are disclosed for treating oral inflammatory disorders. The formulations can act as a bactericide or bacteriostat. The methods include the process associated with the formation of a high temperature polyphenol/surfactant concentrate, a nano-particulate precipitation process in the presence of a surfactant and the solubilization of relatively insoluble aglycone polyphenols/flavonoids by the formation of soluble alkali metal salts within alkaline oral compositions. Also disclosed are compositions that persist in the oral cavity, penetrate teeth, and facilitate or enhance the delivery of chemical elements and active ingredients to teeth for preventing or treating disorders and diseases of the oral cavity. Methods of use, and methods of making, the aforementioned compositions are also disclosed.
申请公布号 US2016074298(A1) 申请公布日期 2016.03.17
申请号 US201514854858 申请日期 2015.09.15
申请人 VIZURI HEALTH SCIENCES LLC 发明人 BIRBARA Philip J.;CUMMINGS Jeffrey S.;GINTER Karl;RAMAN Krishna
分类号 A61K8/49;A61K8/35;C07D311/30;A61Q11/00 主分类号 A61K8/49
代理机构 代理人
主权项 1. A multi-cavity dispensing container for delivering a polyphenol and a toothpaste comprising: a first cavity containing a toothpaste or gel, and a second cavity containing a gel or paste containing a polyphenol.
地址 Fairfax VA US