High Osmolarity Antimicrobial Composition Containing One or More Organic Solvents

摘要

A composition that can solvate biofilms and disrupt bacterial cell walls acts to both kill the bacteria by cell lysis and remove the biofilm. This solvent-containing composition is effective against a broad spectrum of microbes and can be used on a variety of surfaces, both living and inanimate. The polarity of the solvent component of the composition lower than that of pure water so that the composition exhibits increased efficacy in solvating the macromolecular matrix of a biofilm and in penetrating bacterial cell walls.

主权项

1. An antimicrobial composition, comprising:
a) a solvent component that consists essentially of
1) water and2) one or more organic liquids, said solvent component exhibiting a δp value of from 13.1 to 15.7 MPa1/2; and b) a solute component present in an amount sufficient to result in an effective solute concentration of at least about 0.5 Osm/L, said composition optionally having a pH value that is at least 2.0 units away from neutral.