发明名称 METHOD TO IMPROVE LACTOCOCCUS PRESERVATION
摘要 Lactococcus lactis strains with improved preservation characteristics, and improved acid and bile salt tolerance are disclosed. More specifically, a L. lactis strain having a heterologous trehalose-6-phosphate synthase gene and/or a trehalose-6-phosphate phosphatase gene, results in an accumulation of trehalose in the cytoplasm and/or in the cytoplasmic membrane. A L. lactis strain, having an internal trehalose concentration of at least 10 mg per gram cells (w/w) is disclosed.
申请公布号 US2016076044(A1) 申请公布日期 2016.03.17
申请号 US201514934572 申请日期 2015.11.06
申请人 ActoGeniX N.V. 发明人 Remaut Erik;Iserentant Dirk
分类号 C12N15/74 主分类号 C12N15/74
代理机构 代理人
主权项 1. An isolated Lactococcus sp. strain, comprising an internal trehalose concentration of at least 10 mg per gram cells (w/w).
地址 Zwijnaarde BE