| 发明名称 |
APTAMER METHODS AND COMPOSITIONS |
| 摘要 |
Methods of selecting an aptamer that specifically binds to a target molecule complexed with a derivatization agent. Also disclosed are specific aptamers and methods of use thereof. |
| 申请公布号 |
US2016076021(A1) |
申请公布日期 |
2016.03.17 |
| 申请号 |
US201514855171 |
申请日期 |
2015.09.15 |
| 申请人 |
Stojanovic Milan N.;Worgall Tilla S.;Yang Kyung-Ae |
发明人 |
Stojanovic Milan N.;Worgall Tilla S.;Yang Kyung-Ae |
| 分类号 |
C12N15/10;G01N33/53;C12N15/115 |
主分类号 |
C12N15/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for isolating an aptamer specific for a complex comprising a target molecule, the method comprising:
providing a target molecule; providing a derivatization agent; contacting the target molecule and the derivatization agent to form a target complex; providing an oligonucleotide library comprising a plurality of aptamer candidates; contacting the target complex and the oligonucleotide library; and isolating an aptamer that binds to the target complex. |
| 地址 |
Fort Lee NJ US |
