发明名称 |
PROCESS FOR THE PREPARATION OF OPTICALLY ENRICHED ADRENALINE |
摘要 |
A process for the production of (-)-adrenaline and (-)-adrenaline-L-tartrate is provided. The process provides for a new, efficient and commercially feasible process for the optical resolution of racemic adrenaline. In one aspect, a one pot process for the synthesis of (-)-adrenaline is provided. The process provides a simple and less expensive 5 process that can be used to prepare commercial scale batches of (-)-adrenaline and (-)-adrenaline-L-tartrate of API quality. The process avoids the use of expensive and unpredictable chiral catalysts. |
申请公布号 |
WO2016038422(A1) |
申请公布日期 |
2016.03.17 |
申请号 |
WO2014IB64407 |
申请日期 |
2014.09.11 |
申请人 |
ROUVER INVESTMENT S.À.R.L |
发明人 |
PIACENZA, GUY;QUERON, EMMANUELLE |
分类号 |
C07C213/10;C07C215/60 |
主分类号 |
C07C213/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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