发明名称 |
COMPOSITIONS AND METHODS FOR TREATING CANCER RESISTANT TO A TYROSINE KINASE INHIBITOR (TKI) |
摘要 |
Methods of treating a subject having cancer exhibiting a resistance to a tyrosine kinase inhibitor (TKI) are provided. Accordingly, there is provided a method comprising administering to the subject a therapeutically effective amount of antibodies comprising an anti-EGFR antibody, an anti-HER2 antibody and an anti-HER3 antibody. Also provided are compositions and articles of manufacture for treating cancer resistance to a TKI. |
申请公布号 |
WO2016038610(A1) |
申请公布日期 |
2016.03.17 |
申请号 |
WO2015IL50916 |
申请日期 |
2015.09.08 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
YARDEN, YOSEF;MANCINI, MAICOL;GABORIT, NADEGE |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C07K16/30;C07K16/32 |
主分类号 |
C07K16/28 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|