发明名称 |
Bismuth-containing compounds for modulating properties of biologically active agents |
摘要 |
Bismuth-containing compounds include bismuth and a biologically active agent coordinated to the bismuth. The biologically active agent includes at least one heteroatom configured for coordination with the bismuth. Coordination polymers include a polymer matrix that contains a bismuth- containing compound. Methods for modulating a pharmacokinetic property of a biologically active agent include coordinating the biologically active agent to bismuth to form a bismuth-containing compound, and administering the bismuth-containing compound orally to a patient. Methods for treating Parkinson's disease, methods for treating hypothyroidism, methods for treating ulcerative colitis, and methods for treating cancer each include administering a bismuth-containing compound to a patient. |
申请公布号 |
AU2011326137(B2) |
申请公布日期 |
2016.03.17 |
申请号 |
AU20110326137 |
申请日期 |
2011.11.08 |
申请人 |
SYNTHONICS, INC. |
发明人 |
PRICE, JOHN D.;PICCARIELLO, THOMAS;OBERLENDER, ROBERT A.;MULHARE, MICHAELA E.;PALMER, SCOTT B. |
分类号 |
A61K33/24 |
主分类号 |
A61K33/24 |
代理机构 |
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代理人 |
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地址 |
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