发明名称 AQUEOUS FORMULATIONS OF SPARINGLY WATER-SOLUBLE ACTIVE INGREDIENTS COMPRISING AS SOLUBILIZER A MIXTURE OF POLOXAMERS DIFFERING IN HYDROPHOBICITY
摘要 Use of a mixture;a) of a hydroxy-terminated polyether of the block structure (A) (EO)x1′-(PO)y1-(EO)x1″, where y1 is 40 to 70 and (x1′+x1″) is 30-60 and (x1′+x1″)/y1 is less than 1 (component A), and;b) of a hydroxy-terminated polyether of the block structure (B) (EO)x2′-(PO)y2-(EO)x2″, where y2 is 15 to 55 and (x2′+x2″) is 2-50 and (x2′+x2″)/y2 is less than 1 (component B), where (x1′+x1″)/y1 is >(x2′+x2″)/y2, for solubilizing sparingly water-soluble active ingredients, which have a solubility in water of not more than 5 g/l at 25° C. and 0.1013 MPa, in aqueous formulations.
申请公布号 US2016074517(A1) 申请公布日期 2016.03.17
申请号 US201414888951 申请日期 2014.04.25
申请人 BASF SE 发明人 Nguyen-Kim Viet;Marguerre Ann-Kathrin;Mertoglu Murat;Leinenbach Eve Leonie
分类号 A61K47/34;A61K31/216;A01N25/30;A01N43/56;A01N25/02;A61K9/08 主分类号 A61K47/34
代理机构 代理人
主权项
地址 Ludwigshafen DE