| 发明名称 |
Expression Process |
| 摘要 |
A process for the production of a target polypeptide is provided. The process comprises expression of an expression vector for expressing a target polypeptide in a host cell, preferably a mammalian cell, the expression vector comprising an expression cassette comprising a polynucleotide encoding a recombinant polypeptide operably linked to a fibronectin secretion leader sequence; and recovering the target polypeptide. |
| 申请公布号 |
US2016076051(A1) |
申请公布日期 |
2016.03.17 |
| 申请号 |
US201414787669 |
申请日期 |
2014.04.29 |
| 申请人 |
FUJIFILM DIOSYSNTH BIOTECHNOLOGIES UK LIMITED |
发明人 |
Saunders Fay Louise;Dodds Anna Louise;Bayard Adeline Marie Geraldine;Kara Bhupendra Vallabh |
| 分类号 |
C12N15/85;C07K16/06;C07K16/30 |
主分类号 |
C12N15/85 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for the production of a target polypeptide which comprises:
(a) expressing an expression vector for expressing a target polypeptide in a host cell, the expression vector comprising an expression cassette comprising a polynucleotide encoding a recombinant polypeptide operably linked to a fibronectin secretion leader sequence or a functional equivalent thereof; and (b) recovering the target polypeptide. |
| 地址 |
Billingham GB |
