| 摘要 |
The invention comprises the administration of dimeric IgA or pentameric IgM antibodies to animals, including human patients, suffering from a disease state wherein the polymeric immunoglobulin receptor is expressed, such antibodies comprising antibodies that will neutralize one or more growth factors associated with the disease state, or their receptors, in order to diminish the onset, progression, and growth of diseased tissues. The polymeric immunoglobulin receptor is expressed in diseased tissues such as in the apical membranes of cyst-lining cells in polycystic kidney disease. |
