发明名称 |
FLUORESCENCE METHOD FOR SENSING CHLORINATED DISACCHARIDES |
摘要 |
Disclosed are systems for measuring the concentration of a disaccharide in an aqueous medium, the system comprising a boronic acid derivative and a fluorescent molecule. Also disclosed are methods of determining gastrointestinal permeability in a subject, the method comprising contacting an aqueous medium obtained from a subject with the above system to obtain a mixture, where the patient has consumed a known quantity of a disaccharide; measuring the fluorescence emission of the mixture; and correlating the extent of fluorescence emission to the concentration of the disaccharide in the aqueous medium; and correlating the concentration of the disaccharide in the aqueous medium to the gastrointestinal permeability in the subject. Also disclosed are methods of determining the concentration of a disaccharide in an aqueous medium, the method comprising contacting the aqueous medium comprising the disaccharide with the above system to obtain a mixture; measuring the fluorescence emission of the mixture; and correlating the extent of fluorescence emission to the concentration of the disaccharide in the aqueous medium. |
申请公布号 |
WO2015188144(A3) |
申请公布日期 |
2016.03.17 |
申请号 |
WO2015US34557 |
申请日期 |
2015.06.05 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SINGARAM, BAKTHAN;RESENDEZ, ANGEL;WEBB, DOMINIC-LUC |
分类号 |
G01N21/64 |
主分类号 |
G01N21/64 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|