| 发明名称 |
CHEMICALLY TREATED INDUCED PLURIPOTENT STEM CELLS FOR SAFE THERAPEUTIC APPLICATIONS |
| 摘要 |
This disclosure provides a chemically modified induced pluripotent stem (iPS) cells characterized by DNA hypomethylation and methods for generating the cells. The cells are useful in method for or regenerating cardiac muscle tissue or to promote the replacement of cardiac scar tissue in a patient in need thereof and to treat cardiac disease. |
| 申请公布号 |
US2016076001(A1) |
申请公布日期 |
2016.03.17 |
| 申请号 |
US201514951354 |
申请日期 |
2015.11.24 |
| 申请人 |
Ashraf Muhammad |
发明人 |
Ashraf Muhammad |
| 分类号 |
C12N5/074;A61K35/28;A61K31/42;C12N13/00;C12Q1/68 |
主分类号 |
C12N5/074 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A chemically modified induced pluripotent stem (iPS) cell characterized by DNA hypomethylation and that has been derived from a parental cell that has been pre-conditioned by electrical stimulation. |
| 地址 |
Cincinnati OH US |
