| 发明名称 |
Composition with Reduced Immunogenicity |
| 摘要 |
The present invention relates to a composition comprising polyclonal antibodies directed against human cells, wherein the said polyclonal antibodies are devoid of a first antigenic determinant selected in a group comprising (i) N-glycol-neuraminic acid (Neu5Gc) and (ii) α-1,3-galactose and its use as a medicament |
| 申请公布号 |
US2016075770(A1) |
申请公布日期 |
2016.03.17 |
| 申请号 |
US201414785138 |
申请日期 |
2014.04.17 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE |
发明人 |
Soulillou Jean-Paul;Giral Magali;Couvrat-Desvergnes Gregoire |
| 分类号 |
C07K16/18 |
主分类号 |
C07K16/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising polyclonal antibodies directed against human cells, wherein the polyclonal antibodies are devoid of one or both of (i) an N-glycolneuraminic acid (Neu5Gc) antigenic determinant- and (ii) an α-1,3-galactose antigenic determinant. |
| 地址 |
Paris FR |
