TARGETING K-RAS-MEDIATED SIGNALING PATHWAYS AND MALIGNANCY BY PROSTRATIN

摘要

The present invention provides method of treating a K-Ras-expressing cancer in a subject comprising administering to the subject a therapeutic amount of prostratin or a prostratin analog, or a salt or isomer thereof. Compositions and kits for treating a K-Rasexpressing cancer in a subject are also provided.