| 发明名称 |
COMPOUNDS AND COMPOSITIONS AS RAF KINASE INHIBITORS |
| 摘要 |
The present invention provides a compound of Formula (I), wherein X, Y, Z, R1 and R2 are as described herein, and salts thereof and therapeutic uses of these compounds for treatment of disorders associated with RAF kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent. |
| 申请公布号 |
WO2016038581(A1) |
申请公布日期 |
2016.03.17 |
| 申请号 |
WO2015IB56986 |
申请日期 |
2015.09.11 |
| 申请人 |
NOVARTIS AG;BURGER, MATTHEW T.;RAMURTHY, SAVITHRI;TAFT, BENJAMIN R. |
发明人 |
BURGER, MATTHEW T.;RAMURTHY, SAVITHRI;TAFT, BENJAMIN R. |
| 分类号 |
C07D403/12;A61K31/5377;A61P35/00;C07D213/74;C07D413/04;C07D413/14 |
主分类号 |
C07D403/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
