发明名称 |
COMPOSITIONS AND METHOD FOR TREATMENT OF ISCHEMIC NEURONAL REPERFUSION INJURY |
摘要 |
A method and composition for the treatment of ischemic neuronal reperfusion injury are provided. The composition can include a compound which is a combination of dantrolene and a residue of FMOC-valine. This composition can be used to provide a faster and higher CNS penetration than heretofore experienced with dantrolene. In another form, dantrolene may be formulated as a pro-drug, a pro-pro-drug and the like. |
申请公布号 |
EP2994132(A1) |
申请公布日期 |
2016.03.16 |
申请号 |
EP20140794763 |
申请日期 |
2014.05.08 |
申请人 |
HOWARD UNIVERSITY |
发明人 |
MANGAT, HARPAL S.;KARLA, PRADEEP K. |
分类号 |
A61K31/4166;A61P9/10;A61P25/00;A61P43/00;A62B17/00 |
主分类号 |
A61K31/4166 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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