发明名称 組織評価方法
摘要 <P>PROBLEM TO BE SOLVED: To easily and efficiently evaluate an expression level of a specific biological material in a tissue slice to be an object with high accuracy by expressing the specific biological material in the tissue slice as dot-shaped fluorescence that does not depend on the cell morphology thereof. <P>SOLUTION: The tissue evaluation method relating to the invention includes a process for staining a tissue slice by using a stain reagent obtained by combining a spherical particle including a fluorescent material with a biological material recognition site, a stain process for radiating excitation light to the tissue slice to make the tissue slice perform self-fluorescence and make the spherical particle generate dot-shaped fluorescence, an image formation process for forming magnified images of the self-fluorescence and/or the dot-shaped fluorescence, and an evaluation process for detecting the dot-shaped fluorescence in the image that is magnifiedly formed to evaluate an expression level of the biological material corresponding to the biological material recognition site. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP5887823(B2) 申请公布日期 2016.03.16
申请号 JP20110229315 申请日期 2011.10.19
申请人 コニカミノルタ株式会社 发明人 岡田 尚大;郷田 秀樹;高梨 健作;相宮 拓司;中野 寧;権田 幸祐;大内 憲明;渡邉 みか;角森 昭教;石光 義幸
分类号 G01N33/53;G01N21/78;G01N33/48;G01N33/543 主分类号 G01N33/53
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