发明名称 WT1抗原ペプチドコンジュゲートワクチン
摘要 The present invention provides a compound represented by the formula (1): wherein X a and Y a are each a single bond and the like, cancer antigen peptide A is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, R 1 is a hydrogen atom, a group represented by the formula (2): wherein X b and Y b are each a single bond and the like, cancer antigen peptide B has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, or cancer antigen peptide C, and cancer antigen peptide C has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide or an MHC class II-restricted WT1 peptide, consisting of 7 - 30 amino acid residues containing one cysteine residue, or a salt thereof, and the like.
申请公布号 JP5885885(B2) 申请公布日期 2016.03.16
申请号 JP20150508806 申请日期 2014.03.28
申请人 大日本住友製薬株式会社;株式会社癌免疫研究所 发明人 リー、 チャン ジャ;坂 仁志;西尾 幸博;後藤 正志;西原 紀夫;高梨 洋輔
分类号 C07K7/06;A61K39/00;A61P35/00;C07K7/08 主分类号 C07K7/06
代理机构 代理人
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