发明名称 |
COMBINATION OF A PI3 KINASE INHIBITOR WITH PACLITAXEL FOR USE IN THE TREATMENT OR PREVENTION OF A CANCER OF THE HEAD AND NECK |
摘要 |
A pharmaceutical combination comprising (a) a phosphatidylinositol-3-kinase (PI3K) inhibitor compound of formula (I), as defined herein, or a pharmaceutically acceptable salt thereof and (b) paclitaxel or a pharmaceutically acceptable salt thereof for simultaneous, separate or sequential use, for the treatment of a cancer of the head and neck; a pharmaceutical composition comprising said combination; the use of said combination for the preparation of a medicament for the treatment of a cancer of the head and neck; a method of treating or preventing a cancer of the head and neck comprising administering a jointly therapeutically effective amount of such a combination to a subject in need thereof; and a commercial package thereof. |
申请公布号 |
EP2994126(A1) |
申请公布日期 |
2016.03.16 |
申请号 |
EP20140731782 |
申请日期 |
2014.05.06 |
申请人 |
NOVARTIS AG |
发明人 |
HIRAWAT, SAMIT;MASSACESI, CRISTIAN;DI TOMASO, EMMANUELLE |
分类号 |
A61K31/337;A61K31/506;A61P35/00 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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