发明名称 BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS
摘要 This application relates to chemical compounds which may act as inhibitors of; or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2, R2b, R3, R4a, R4b, and R5 are described herein.
申请公布号 EP2994469(A1) 申请公布日期 2016.03.16
申请号 EP20140729182 申请日期 2014.05.08
申请人 GILEAD SCIENCES, INC. 发明人 AKTOUDIANAKIS, EVANGELOS;CHIN, GREGORY;CORKEY, BRITTON KENNETH;DU, JINFA;ELBEL, KRISTYNA;JIANG, ROBERT H.;KOBAYASHI, TETSUYA;LEE, RICK;MARTINEZ, RUBEN;METOBO, SAMUEL E.;MISH, MICHAEL;MUNOZ, MANUEL;SHEVICK, SOPHIE;SPERANDIO, DAVID;YANG, HAI;ZABLOCKI, JEFF
分类号 C07D413/04;A61K31/422;A61P35/00;C07D413/14;C07D417/14 主分类号 C07D413/04
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