发明名称 |
BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS |
摘要 |
This application relates to chemical compounds which may act as inhibitors of; or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2, R2b, R3, R4a, R4b, and R5 are described herein. |
申请公布号 |
EP2994469(A1) |
申请公布日期 |
2016.03.16 |
申请号 |
EP20140729182 |
申请日期 |
2014.05.08 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
AKTOUDIANAKIS, EVANGELOS;CHIN, GREGORY;CORKEY, BRITTON KENNETH;DU, JINFA;ELBEL, KRISTYNA;JIANG, ROBERT H.;KOBAYASHI, TETSUYA;LEE, RICK;MARTINEZ, RUBEN;METOBO, SAMUEL E.;MISH, MICHAEL;MUNOZ, MANUEL;SHEVICK, SOPHIE;SPERANDIO, DAVID;YANG, HAI;ZABLOCKI, JEFF |
分类号 |
C07D413/04;A61K31/422;A61P35/00;C07D413/14;C07D417/14 |
主分类号 |
C07D413/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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