The present invention relates to a method of assessing whether a subject mammal has a target condition, comprising a step of formulating a function of abundances of a first group of biomarkers and abundances of a second group of biomarkers that is useful for assessing whether the subject mammal has the target condition. The present invention also relates to a computer-aided system for assessing whether a subject mammal has a target condition. The present invention further relates to a computer-readable medium for assessing whether a subject mammal has a target condition