| 摘要 |
The present invention provides 3-(4-ethynylphenyl)pyridopyrimidinone compounds of formula A as potential anticancer agents. 3-(4-ethynylphenyl)pyridopyrimidinone compounds have shown promising anticancer activity in various cell lines sixty human cancer cell lines. [Formula A] Wherein [Formula B] R1═H, OH, OCH3R2═H, OH, CH3, OCH3, NO2R3═H, OH, OCH3, F, CIR4═H, OH, CH3, OCH3R5═H, OH, CH3, OCH3R6═H, OCH3 R2+R3=-0CH2O— |
