发明名称 |
MICROFLUIDIC DEVICES AND METHODS FOR PERFORMING SERUM SEPARATION AND BLOOD CROSS-MATCHING |
摘要 |
Microfluidic cartridges or devices for serum separation and blood cross-match analysis are provided. The devices may include a serum separation subcircuit alone or in combination with a solute mixing subcircuit. The serum separation subcircuit promotes on-cartridge clotting of a blood sample and manipulates the flow of the separated serum sample for subsequent cross-match analysis with a second blood sample, for example. The solute mixing subcircuit includes at least two intake channels, one for a whole blood sample from, for example, a blood donor and the other for the separated serum sample from, for example, a transfusion recipient. The solute mixing subcircuit further includes a serpentine mixing channel conjoined to a downstream channel. Under vacuum generated by a conjoined finger pump, the two input streams fill the serpentine mixing and downstream channels due to capillary action, enabling visualization of an agglutination reaction. |
申请公布号 |
EP2994750(A1) |
申请公布日期 |
2016.03.16 |
申请号 |
EP20140794854 |
申请日期 |
2014.05.07 |
申请人 |
MICRONICS, INC. |
发明人 |
KOLB, ANDREW, W.;ELMUFDI, CAROLINA, L.;BATTRELL, C., FREDERICK |
分类号 |
G01N33/80;B01L3/00;G01N33/49 |
主分类号 |
G01N33/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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