Transformant and process for production thereof, and process for production of lactic acid

摘要

The present invention relates to a transformant, containing a lactate dehydrogenase gene which is introduced into Schizosaccharomyces pombe as a host, in which a part of a gene cluster encoding a pyruvate decarboxylase in the Schizosaccharomyces pombe host is deleted or inactivated.

主权项

1. A Schizosaccharomyces pombe transformant, wherein the transformant is transformed with a lactate dehydrogenase gene, wherein the chromosomal pyruvate decarboxylase (PDC) 2 gene in the transformant is deleted or inactivated, wherein the chromosomal PDC 4 gene in the transformant is not deleted or inactivated, and wherein the transformant produces lactic acid at a pH of 3.5 or less, while maintaining ethanol production suitable for growth of the transformant.