Immunoglobulin-binding polypeptide

摘要

An object of the present invention is to provide novel polypeptides that are capable of binding to an immunoglobulin and have high stability against alkali. The present invention relates to proteins having the amino acid sequence of SEQ ID No:1 or 2.

主权项

1. A polypeptide, that binds to a protein comprising an Fc region of an immunoglobulin, the polypeptide comprising the following amino acid sequence:(SEQ ID NO: 47)RFX1X2EQQNAFYEILHX3PNLTEEQRNX4FIQX5LX6X7X8PSVSREX9LAEAX10X11LNDAQAPX12 wherein X1 is D, E, N, or Q; X2 is E or R; X3 is L, M, or I; X4 is A, E, F, R, Y, or W; X5 is D, E, H, I, L, Q, R, S, T, or V; X6 is H, I, or R; X7 is D, I, or R; X8 is D or E; X9 is I, L, or V; X10 is R or Q; X11 is H or R; and X12 is R, G, or K.